| 第 35 卷第 4 期 |  | Vol. 35 No. 4 | | 2005 年 8 月 | Aug 2005 |
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所属栏目：农药及中间体
氟咯草酮的合成研究 |
| 杨剑波; 庞怀林; 黄超群(湖南化工研究院; 湖南长沙) |
| 摘 要：以N-烯丙基-间-三氟甲基二氯乙酰苯胺为原料,在催化剂作用下重排制得氟咯草酮,对反应条件进行了研究,得出了合成氟咯草酮及相关中间体的优惠条件为:铜催化剂用量的7.5g/mol,反应温度110℃,反应时间3h。中间体N-烯丙基-间-三氟甲基苯胺的反应收率超过90%,N-烯丙基-间-三氟甲基-二氯乙酰替苯胺的收率超过95%,氟咯草酮的收率超过85%,产品纯度超过90%。 |
| 关键词：除草剂; 氟咯草酮; N-烯丙基-3-三氟甲基-二氯乙酰替苯胺; 二氯乙酰氯; N-烯丙基-间三氟甲基苯胺 |
| 中图分类号：TQ457 文献标识码：A 文章编号：1009-9212(2005)04-0024-04 |
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| Synthesis of Herbicide Fluorochloridone |
| YANG Jian-bo; PANG Huai-lin; HUANG Chao-qun （Hunan Research Institute of Chemical Industry; Changsha 410007; China） |
| Abstract：The Herbicide Fluorochloridone [3-chloro-4-(chlorometheyl)-1-[3-(trifluoromethyl) phenyl]-2-pyrrolidinone] was prepared from 2,2-dichloro-N-2-propenyl-N- [3-(trifluoromethyl) phenyl]-acetamide in the presence of catalyst, and the optimal reaction conditions of Fluorochloridone and its intermediates were obtained in the laboratory.The optimum conditions of Fluorochloridone was as follow,reaction temperature 110℃,reaction time 3 h ,the amount of Cu catalyst 7.5 g/mol.The yield of the intermediate N-(2-propeny... |
| Key words：synthesis; fluorochloridone; 3-trifluoromethylaniline; dichloroacethyl chloride; 3-chloro- propylene |
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收稿日期：2005-05-07
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